![]() ![]() Because both daughter DNA strands are polymerized in the 5’ to 3'direction, the DNA synthesized on the lagging strand must be made initially as a series of short DNA molecules, called Okazaki fragments. The original strands therefore remain intact through many cell generationsĥ The structure of a DNA replication fork In a round of replication, each of the two strands of DNA is used as a template for the formation of a complementary DNA strand. As shown, base-pairing between an incoming deoxyribonucleoside triphosphate and an existing strand of DNA (the template strand) guides the formation of the new strand of DNA and causes it to have a complementary nucleotide sequence.Ĥ Review : Replication The semiconservative nature of DNA replication. The addition of a deoxyribonucleotide to the 3' end of a polynucleotide chain (the primer strand) is the fundamental reaction by which DNA is synthesized. ![]() ![]() In this way, a double-helical DNA molecule can be copied preciseģ Review : Replication The chemistry of DNA synthesis. Because the nucleotide A will pair successfully only with I and G only with C, each strand of DNA can serve as a template to specify the sequence of nucleotides in its complementary strand by DNA basepairing. 2 Review : Replication The DNA double helix acts as a template for its own duplication. ![]()
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